Nov 13 2025
Why Does PMS Get Worse With Age?
The core of PMS lies in the dramatic shift between estrogen and progesterone in the luteal phase. As women approach their late 30s and 40s (the perimenopausal transition), ovarian function begins to decline. Instead of a smooth decline, hormone secretion becomes erratic. This instability especially in progesterone, which has a calming effect can lead to severe mood swings.
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